Purine nucleosides
Sigma Aldrich Fine Chemicals Biosciences 23 Dideoxyguanosine 5 trip2MG
23 Dideoxyguanosine 5 trip2MG
Apexbio Technology LLC Cordycepin 73-03-0 20mg
Cordycepin (73-03-0) is a small-molecule inhibitor targeting pro-inflammatory cytokines such as IL-1 IL-6 and TNF- It is designed to inhibit inflammatory signaling pathways thereby regulating immune and inflammatory responses Cordycepin exerts its biological activity primarily through interference with RNA synthesis by incorporation into RNA chains leading to premature termination and inhibition of protein translation In cell-based studies cordycepin demonstrates inhibitory activity with IC50 values in the low micromolar range (approximately 5-15 M) depending on experimental conditions and cell models Based on these pharmacological properties cordycepin holds research potential in inflammation regulation immune-response modulation tuberculosis infection modeling and RNA transcription studies
TARGETMOL CHEMICALS INC 5-FLUORO-5-DEOXYADENOSIN 5MG
Also available in 1 mg 2 mg 10 mg 25 mg 50 mg 100 mg 500 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. 5'-Fluoro-5'-deoxyadenosine (5'-Fluoro-5'-deoxy-adenosine) is utilized commonly as a tool for studying the Actinomycete bacterium Streptomyces cattleya. purity: 97%
Bioworld 2'-Deoxyadenosine Monohydrate, 5 g
A deoxyribonucleoside, may be used by some cells as an energy source under energy stress conditions and to affect cAMP levels. It is used in comparison studies of the functions of adenosine analogues on various biological processes. Specifications:Ultra Pure GradeEM (259nm, phosphate buffer, pH 7.0): >14,500Appearance: White crystalline powderChEBI : Not available.Crystal_Structure : Not available.InChI : Not available.InChIKey : Not available.Melting Point: 187-189 °CRTECS Number: AU7358600
Medchemexpress LLC 3′-Deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 50 MG
3′-Deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 50 MG
Medchemexpress LLC 7-deaza-2'-deoxyadenosine | 60129-59-1 | 99.9% | 250.26 g/mol | C11H14N4O3 | 1 ML
7-deaza-2'-deoxyadenosine is a deoxynucleoside used as a biochemical reagent and building block for synthesis and oligonucleotide research.
- Ready-to-use 10 mM solution in DMSO.
- Supplied as 1 mL vial.
- High purity, reported as 99.9%.
- Molecular weight 250.26 g/mol.
- Molecular formula C11H14N4O3.
- CAS number 60129-59-1 for unambiguous identification.
Medchemexpress LLC 3′-Deoxyguanosine | 3608-58-0 | 97.0% | 267.25 | 5 MG
3′-Deoxyguanosine is a derivative of Guanosine. It interacts with human purine nucleoside phosphorylase through hydrogen bonding with residues like Glu201 and Asn243. This compound shows moderate displacement activity for [3H]-guanosine in rat meninges and is useful for studying the mechanism of guanosine receptors and purine metabolism.
- Derivative of Guanosine.
- Interacts with human purine nucleoside phosphorylase via hydrogen bonding.
- Exhibits moderate displacement activity for [3H]-guanosine in rat meninges.
- Useful for studying guanosine receptor mechanisms and purine metabolism.
- For research use only.
TARGETMOL CHEMICALS INC 5-Amino-5-deoxyadenosine 5MG
Also available in 10 mg, 25 mg, 50 mg and bulk. Please contact Fisher for quotes. 5'-Amino-5'-deoxyadenosine (NH2dAdo) is an adenosine kinase inhibitor targeting malignant tumors of the inert lymphatic system with antitumor and anticancer effects. Its mechanism is mediated by the inhibition of DNA synthesis and induction of apoptosis. Purity 95.55%
Medchemexpress LLC 2'-Deoxyguanosine | 961-07-9 | 100.0% | 267.25 | 25 MG
2'-Deoxyguanosine is a purine nucleoside with various biological activities. It can induce DNA division in mouse thymus cells and acts as a potent cell division inhibitor in plant cells. It also demonstrates antiproliferative and antiviral effects against several cell lines and viruses.
- Induces DNA division in mouse thymus cells.
- Acts as a potent cell division inhibitor in plant cells.
- Inhibits clonal growth of HL-60 and K562 leukemia cells.
- Exhibits antiviral activity against varicella zoster virus (VZV) Oka strain.
- Exhibits antiviral activity against human cytomegalovirus (HCMV) AD 169 strain.
- Exhibits antiviral activity against herpes simplex virus-1 VR-3 strain.
- Exhibits antiviral activity against herpes simplex virus-2 (HSV-2) Ms strain.
Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 50 MG
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase. It causes rapid cell death for the majority of cancer cell lines tested with IC50s between 0.7-2.9 μM. In A549 lung cancer cell-based mouse xenograft studies, it decreases tumor growth rate and increases telomere dysfunction in tumor cells in vivo.
- Nucleoside analogue
- Incorporated into de novo-synthesized telomeres by telomerase
- Results in rapid cell death for the vast majority of cancer cell lines tested with IC50s of between 0.7-2.9 μM
- Causes a decrease of the tumor growth rate in A549 lung cancer cell-based mouse xenograft studies
- Increases telomere dysfunction in tumor cells in vivo
Medchemexpress LLC Guanosine-1',2,2',3',4,4',5,5',6,8-13C10, 2'-deoxy- | 1245539-86-9 | 99.8% | 277.17 | 1 MG
2'-Deoxyguanosine-13C10 is a 13C-labeled version of 2'-Deoxyguanosine. It is a purine nucleoside with various biological activities, capable of inducing DNA division in mouse thymus cells and acting as a cell division inhibitor in plant cells. In vitro, it inhibits the clonal growth of HL-60 and K562 leukemia cells.
- 13C-labeled version of 2'-Deoxyguanosine
- Induces DNA division in mouse thymus cells
- Potent cell division inhibitor in plant cells
- Inhibits clonal growth of HL-60 and K562 leukemia cells
Medchemexpress LLC 6-Thio-2'-Deoxyguanosine | 789-61-7 | 99.7% | 283.31 | 10 MM * 1 ML
6-Thio-2'-Deoxyguanosine is a nucleoside analogue that can be incorporated into de novo-synthesized telomeres by telomerase.
- Nucleoside analogue
- Can be incorporated into de novo-synthesized telomeres by telomerase
- Rapid cell death for the vast majority of cancer cell lines tested with IC50s of between 0.7-2.9 μM (in vitro)
- Causes a decrease of the tumor growth rate in A549 lung cancer cell-based mouse xenograft studies, superior to that observed with 6-thioguanine treatment (in vivo)
- Increases telomere dysfunction in tumor cells in vivo
- Appearance: Solid
- Color: White to yellow
Medchemexpress LLC 2'-deoxyadenosine-5'-monophosphate | 653-63-4 | MFCD00005753 | 99.6% | 331.23 | C10H14N5O6P | 10 MG
2'-Deoxyadenosine-5'-monophosphate is a deoxyribonucleotide used as a reference standard and reagent in nucleic acid research, analytical assays, and enzymology studies. It is supplied as a white to off-white solid with high reported purity and accompanying analytical documentation.